François David Selected Research

Cyclic Nucleotide-Gated Cation Channels

1/2021	Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures.
1/2018	Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures.

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François David Research Topics

Disease

4	Seizures (Absence Seizure) 01/2021 - 01/2016
3	Absence Epilepsy (Childhood Absence Epilepsy) 01/2021 - 01/2016
1	Heart Failure 01/2021
1	Neurodevelopmental Disorders 01/2020
1	Kleefstra Syndrome 01/2020
1	Autism Spectrum Disorder 01/2020
1	Epilepsy (Aura) 01/2020
1	Sleep Wake Disorders 01/2015

Drug/Important Bio-Agent (IBA)

2	Cyclic Nucleotide-Gated Cation ChannelsIBA 01/2021 - 01/2018
2	Cyclic NucleotidesIBA 01/2021 - 01/2018
1	ElacridarIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	IvabradineIBA 01/2021
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2021
1	Histone MethyltransferasesIBA 01/2020
1	ChromatinIBA 01/2020
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2020
1	GABA Plasma Membrane Transport ProteinsIBA 01/2020
1	ICI D2788IBA 01/2018
1	ElementsIBA 01/2018
1	Serotonin 5-HT2 Receptor AntagonistsIBA 01/2016
1	LigandsIBA 01/2016
1	Serotonin (5 Hydroxytryptamine)IBA 01/2016

Therapy/Procedure

3	Therapeutics 01/2020 - 01/2015
1	Oral Administration 01/2021